| Scientists
have known the existence of Human Growth
Hormone as early as the 1920s. It was not
until 1958 before they began to apply HGH on
children that suffer from dwarfism to help
them grow normally. The effects were very
obvious. The theory behind the use of HGH in
those days was that the pituitary gland, which
secrets HGH, was either defective or not
functioning at all in those children with
dwarfism. The main source of HGH for treatment
at that time was extracted from the pituitary
glands of dead people in Africa. It often took
thousands of brains of the dead to produce
just a few drops of HGH! Scientists were,
therefore, forced to research alternatives
such as synthetic HGH. In 1985, Genentech
succeeded in producing large quantities of HGH
through microbiological replication by
inserting human DNA into microorganisms. HGH
has 191 amino acids. Genentech was able to
produce HGH with 191 amino acids by using
bio-engineering of the genes.
In
1985, Dr. Daniel Rudman, a Wisconsin internal
medicine scholar, first published in the
Journal of American Geriatrics Society a brand
new theory about aging based on his many years
of extensive clinical experiments and
research. He indicated clearly in the article
that human aging is a result of HGH
deficiency, and is not the commonly accepted
view of "inevitable natural
phenomenon." He further concluded that by
stimulating the pituitary gland with HGH, the
gland could be made to recover its function to
secrete HGH again. This discovery not only
stops the aging process but also turns back
the biological clock to its adolescent stage.
In
July 1990, Dr. Daniel Rudman published another
article in the New England Journal of Medicine
that shocked the entire medical fields. This
article became a milestone in anti-aging
treatment with the clinical trials of HGH. He
selected 12 males, aged from 61 to 81 for
treatment. After 6 months' use of HGH, their
fat was reduced by 14.4%; skin thickness
increased 7.11%; bone density increased 1.6%;
liver improved 19% and spleen improved 17%.
Dr. Rudman concluded that these 12 old men had
become younger by 20 years both physically and
psychologically.
Encouraged
by Dr. Rudman's HGH theory, the National
Institute on Aging began in 1992 to carry out
nine clinical experiments that took 5 years to
complete. The results, unprecedented and
far-reaching in influence, proved once again
that Dr. Rudman's theory was correct.
In
1996 Dr. Rudman had over 800 HGH patients,
including movie stars, corporate executives,
other renowned doctors, specialists and
scholars. In his medical reports, he indicated
that among thousands of patients, there was
not even one single case of failure.
Within
the past ten years, there were more than
30,000 case reports, the results were very
encouraging. In 1996, FDA finally approved the
usage of HGH in the treatment of both children
and adults for suffering from growth hormone
deficiency. It is now recognized in the
medical fields that HGH is the major hormone
among all hormones. It guides and promotes the
release and secretion of other hormones.
To
make HGH popular and easier to use, an oral
delivery system has been developed. It takes
advantage of the short distance between the
brain and the mouth so that HGH can pass
through the mucous membrane under the tongue
into the blood vessels within seconds, then it
goes directly into the brain. It is quickly
absorbed and works to stimulate and reactivate
the functions of the pituitary gland to
secrete HGH and other rejuvenating hormones.
Due to its low but proper dosage, there are no
side effects. It is also affordable based on
its reasonable price.
HOMEOPATHIC HGH IN MEDICAL PRACTICE
Dr. Diane A. Culik, M.D. and
Dr. Gary Docks
January, 2000
Background:
A homeopathic formulation
of human growth hormone (produced by Dr.
Sidney Safron) has been used with reports of
increased: energy, vigor, stamina, sex drive,
muscle tone, sleep, memory and reduced:
fatigue, and headache. The natural levels of
human growth hormone fall with increased age
and have been blamed for progressive loss of
youthful energy, and many of the symptoms of
aging. Rejuvenate 2000 has devised 4 different
homeopathic formulations which vary for age
and sex, with additional herbs and minerals
added
Study
Hypothesis:
A study was devised to test
the clinical response to the homeopathic HGH
formulation, as well as measure the changes in
Free IGF-1 in saliva, to determine if
measurable changes in body chemistry were
occurring as predicted, and if the patient's
symptoms correlated
Study
Design:
The study was designed to
evaluate treatment with 4 subtypes of MORE HGH,
including women age 25-50 and women over 50,
as well as men age 25-50 and men over 50. The
study was double blinded so that neither the
patient nor the physician knew which numbers
of the sample bottles were homeopathic HGH
produced by Dr. Safron and which were placebo
(which was only an alcohol solution). All
patients volunteered to be in the study and
were given a symptom checklist at the
beginning and end of the one month treatment.
They self ranked 10 symptom complexes from 1
to 10. The symptoms to be rated included:
vision, skin condition, energy level, blood
pressure, muscle strength, mental clarity,
memory retention, joint movement, sleeping
pattern, and overall health. All patients (who
were required to be non-smokers) did a saliva
sample at the beginning and end of the one
month to measure for IGF-1, which is increased
by growth hormone. Therapeutic, pharmaceutical
doses have been shown to increase the levels.
It was not clear how much impact there would
be with homeopathic doses. The method of
taking the homeopathic HGH was somewhat
involved and required patient compliance.
Instead of a typical pill, homeopathic
treatments are often taken sublingually, so
that the small amounts of solution are
absorbed directly through the mucous membranes
under the tongue and into the circulation. The
growth hormone solution was prescribed to be
taken before food by placing 7 drops under the
tongue three times a day and holding the
solution there for at least 2 minutes before
swallowing
Results:
35 people enrolled in the
study, 16 men and 19 women. The men were
equally divided. 8 of them were 25-50 and 8
were 50 and older. Of the women, 8 were 25-50
and 11 were 50 or older. Only 19 people
completed all parts of the study including 2
questionnaires and 2 saliva tests. The
measurements of IGF-1 in the saliva rose an
average of 4.12% in the placebo group and
10.02% in the HGH group, which is a 2.4 times
increase from placebo to treatment group. The
patient's self-reported symptoms were
considered a significant change if they varied
more than one point (or 10%). Therefore, if
they changed from a rating of 5 to 6 it was
considered within the normal statistical
variant. Only changes of 2 levels, such as
going from 5 to 7 were considered significant
in the evaluations. Measurements were then
compared between groups as plus or minus 20,
30, 40 points, etc. The symptoms that showed
significant improvement in average ratings
between placebo and human growth hormone
TREATMENT groups included in descending order:
vision (+11.16), skin condition(+11.03),
energy levels(+11.03), overall health(+10.0),
muscle strength(+8.97), joint movement(+6.1),
and memory retention(+4.42). The areas with no
significant difference were: blood
pressure(+.65), mental clarity(-.78), and
sleeping pattern(-2.47). The only symptom that
was somewhat higher in the placebo group than
in the treatment group was sleep pattern
Discussion:
This was a small
preliminary double-blind study meant to
determine if homeopathic human growth hormone
can show any objective changes in measurement
of Salivary IGF-1 OR any clinical symptom
changes over a one month period of time in a
group of patient volunteers of both sexes over
age 25. Both of the study measurements
definitely show an effect of this Homeopathic
formulation over a short period of time. The
significant rise in measurable IGF-1 on the
Saliva of 2.4 times the placebo effect is
definitely dramatic, especially with a
treatment that requires considerable
compliance. Absolute adherence to the dosing
and technique would probably show even higher
differential. Several patients reported
dramatic improvements in multiple areas while
using the REAL HGH. Perhaps many of the High
Responders were more precise and accurate in
their taking of the homeopathic formulation.
Certainly the patients who dropped out often
did so for lack of interest and compliance.
The symptom improvement was higher in the
treatment group for 9 out of 10 variables.
This is dramatic in only 1 month. 7 of the 10
symptoms were significantly higher with the
treatment group. It is of interest that the
only benefit of placebo over treatment group
was in sleep pattern, since the placebo was
primarily an alcohol solution
Summary
This study calls for
further investigation into this homeopathic
formulation of Human Growth Hormone,
(Rejuvenate 2000's HGH) since it has proven chemical
and clinical significance within a small group
of men and women over a one month experience.
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